What is a common side effect associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs)?

The correct answer highlights gastrointestinal irritation as a common side effect of non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by inhibiting enzymes involved in the inflammatory process, but in doing so, they can also affect the lining of the stomach and intestines. This can lead to symptoms such as stomach pain, indigestion, and potentially more serious conditions such as ulcers or gastrointestinal bleeding, especially with long-term use or high doses.

Understanding this effect is crucial for patients and healthcare providers, as it emphasizes the importance of monitoring and possibly administering protective agents, like proton pump inhibitors, if NSAIDs are prescribed for chronic conditions. This awareness is vital in managing treatment plans and minimizing risks associated with NSAID therapy.