Which class of medications works on the central nervous system to control vomiting?

The class of medications that specifically works on the central nervous system to control vomiting is antiemetics. These medications act primarily on the brain and gastrointestinal tract to counteract the signals that trigger nausea and vomiting. They can target various pathways in the brain, including dopamine and serotonin receptors, to alleviate these symptoms.

Antiemetics are commonly used in various clinical settings, such as for patients undergoing chemotherapy, those experiencing motion sickness, or individuals recovering from surgery, where nausea and vomiting are often side effects. This class includes drugs like ondansetron and metoclopramide, which are designed to manage these symptoms effectively.

In contrast, the other medication classes listed do not focus on controlling vomiting. Antidepressants are primarily used to treat mood disorders, analgesics relieve pain, and antihypertensives manage high blood pressure. None of these serve the specific purpose of alleviating nausea or vomiting through action on the central nervous system.